abstract：:The expression of corticosteroids and regional expression 16 (CR16) and neural Wiscott-Aldrich syndrome protein (N-WASP) was studied in the testes of men with idiopathic azoospermia by (1) immunohistochemistry and Western blot to detect the expression of CR16 and N-WASP protein, (2) reverse transcription with the poly...

journal_title：Cell and tissue research

authors： Xiang W,Wen Z,Pang W,Hu L,Xiong C,Zhang Y

更新日期：2011-06-01 00:00:00

abstract：:Putative neural stem cells have been identified within the enteric nervous system (ENS) of adult rodents and cultured from human myenteric plexus. We conducted studies to identify neural stem cells or progenitor cells within the submucosa of adult human ENS. Jejunum tissue was removed from adult human subjects undergo...

journal_title：Cell and tissue research

authors： Azan G,Low WC,Wendelschafer-Crabb G,Ikramuddin S,Kennedy WR

更新日期：2011-05-01 00:00:00

abstract：:The complex physiology of the gastrointestinal (GI) tract must permanently be adjusted according to the composition of ingested food, which requires continuous monitoring by appropriate sensory systems. Sensing the dietary constituents is thought to be mediated by chemosensory cells residing in the mucosa of the GI tr...

journal_title：Cell and tissue research

authors： Sothilingam V,Hass N,Breer H

更新日期：2011-05-01 00:00:00

abstract：:Transcriptome profiling of the pineal gland has revealed night/day differences in the expression of a major fraction of the genes active in this tissue, with two-thirds of these being nocturnal increases. A set of over 600 transcripts exhibit two-fold to >100-fold daily differences in abundance. These changes appear t...

journal_title：Cell and tissue research

authors： Bustos DM,Bailey MJ,Sugden D,Carter DA,Rath MF,Møller M,Coon SL,Weller JL,Klein DC

更新日期：2011-04-01 00:00:00

abstract：:Changes in intestinal function, notably impaired transit, following ischemia/reperfusion (I/R) injury are likely to derive, at least in part, from damage to the enteric nervous system. Currently, there is a lack of quantitative data and methods on which to base quantitation of changes that occur in enteric neurons. In...

journal_title：Cell and tissue research

authors： Rivera LR,Thacker M,Pontell L,Cho HJ,Furness JB

更新日期：2011-04-01 00:00:00

abstract：:Calbindin is a calcium-binding protein, commonly found in certain subpopulations of the enteric nervous system in mammals. Recently, calbindin-immunoreactive enteric neurons have also been demonstrated in shorthorn sculpin (Myoxocephalus scorpius). In the present study, calbindin immunoreactivity has been investigated...

journal_title：Cell and tissue research

authors： Olsson C

更新日期：2011-04-01 00:00:00

abstract：:We have developed a simple and reliable method of preserving antigen immunoreactivity with concomitant excellent retention of the cell ultrastructure. Using this method, we have been able to follow the origin and developmental stages of nuage accumulations within the nurse cell/oocyte syncytium in the ovary of the fru...

journal_title：Cell and tissue research

authors： Jaglarz MK,Kloc M,Jankowska W,Szymanska B,Bilinski SM

更新日期：2011-04-01 00:00:00

abstract：:Collagens are the most abundant proteins in vertebrate tissues and constitute significant moieties of the extracellular matrix (ECM). The determination of the collagen content is of relevance not only in the field of native tissue research, but also regarding the quality assessment of bioengineered tissues. Here, we d...

journal_title：Cell and tissue research

authors： Nimptsch A,Schibur S,Ihling C,Sinz A,Riemer T,Huster D,Schiller J

更新日期：2011-03-01 00:00:00

abstract：:Eosinophils are innate immune leukocytes found in relatively low numbers within the blood. Terminal effector functions of eosinophils, deriving from their capacity to release their content of tissue-destructive cationic proteins, have historically been considered primary effector mechanisms against specific parasites,...

journal_title：Cell and tissue research

authors： Shamri R,Xenakis JJ,Spencer LA

更新日期：2011-01-01 00:00:00

abstract：:Infection by influenza virus leads to respiratory failure characterized by acute lung injury associated with alveolar edema, necrotizing bronchiolitis, and excessive bleeding. Severe reactions to infection that lead to hospitalizations and/or death are frequently attributed to an exuberant host response, with excessiv...

journal_title：Cell and tissue research

authors： Sanders CJ,Doherty PC,Thomas PG

更新日期：2011-01-01 00:00:00

abstract：:During tooth development, the inner and outer enamel epithelia fuse by mitotic activity to produce a bilayered epithelial sheath termed Hertwig's epithelial root sheath (HERS). The epithelial rests of Malassez (ERM) are the developmental residues of HERS and remain in the adult periodontal ligament (PDL). Although the...

journal_title：Cell and tissue research

authors： Korkmaz Y,Klinz FJ,Beikler T,Blauhut T,Schneider K,Addicks K,Bloch W,Raab WH

更新日期：2010-12-01 00:00:00

abstract：:Histological characterization of spinal fusions in Atlantic salmon (Salmo salar) has demonstrated shape alterations of vertebral body endplates, a reduced intervertebral space, and replacement of intervertebral cells by ectopic bone. However, the significance of the notochord during the fusion process has not been add...

journal_title：Cell and tissue research

authors： Ytteborg E,Torgersen JS,Pedersen ME,Baeverfjord G,Hannesson KO,Takle H

更新日期：2010-12-01 00:00:00

abstract：:1α,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)] induces osteoclast formation via induction of receptor activator of NF-κB ligand (RANKL, also called TNF-related activation-induced cytokine: TRANCE) in osteoblasts. In cocultures of mouse bone marrow cells and osteoblasts, 1,25(OH)(2)D(3) induced osteoclast formation in a...

journal_title：Cell and tissue research

authors： Tachi K,Takami M,Zhao B,Mochizuki A,Yamada A,Miyamoto Y,Inoue T,Baba K,Kamijo R

更新日期：2010-11-01 00:00:00

abstract：:Fibroblast growth factors (Fgfs) are proteins with diverse functions in development, repair, and metabolism. The human Fgf gene family with 22 members can be classified into three groups, canonical, intracellular, and hormone-like Fgf genes. In contrast to canonical and intracellular Fgfs identified in invertebrates a...

journal_title：Cell and tissue research

authors： Itoh N

更新日期：2010-10-01 00:00:00

abstract：:Mesenchymal stromal cells (MSCs), especially those lying close to cartilage defects, are an important cell source for cartilage regeneration. We hypothesize that a larger number of MSCs might become available, if the bone marrow in the immediate vicinity of the subchondral bone is stimulated for MSCs in advance of the...

journal_title：Cell and tissue research

authors： Nishizawa K,Imai S,Mimura T,Kubo M,Araki S,Shioji S,Takemura Y,Matsusue Y

更新日期：2010-09-01 00:00:00

abstract：:Successful embryo implantation depends on intricate epithelial-stromal cross-talk. However, molecular modulators involved in this cellular communication remain poorly elucidated. Using multiple approaches, we have investigated the spatiotemporal expression and regulation of serine protease inhibitor Kazal type 3 (SPIN...

journal_title：Cell and tissue research

authors： Chen W,Han BC,Wang RC,Xiong GF,Peng JP

更新日期：2010-09-01 00:00:00

abstract：:In situ hybridisation and immunohistochemistry analyses have shown that the Ciona intestinalis tumour necrosis factor alpha gene (CiTNFalpha), which has been previously cloned and sequenced, is expressed either during the inflammatory pharynx response to lipopolysaccharide (LPS) or during the swimming larval phase of ...

journal_title：Cell and tissue research

authors： Parrinello N,Vizzini A,Salerno G,Sanfratello MA,Cammarata M,Arizza V,Vazzana M,Parrinello D

更新日期：2010-08-01 00:00:00

abstract：:Interstitial cells of Cajal (ICC) are morphologically and functionally intercalated between the elements of the enteric nervous system and the smooth muscle cells (SMCs) in the musculature of the digestive tract. Kit immunohistochemistry reliably identifies the location of these cells and provides information on chang...

journal_title：Cell and tissue research

authors： Radenkovic G,Ilic I,Zivanovic D,Vlajkovic S,Petrovic V,Mitrovic O

更新日期：2010-06-01 00:00:00

abstract：:Black tiger shrimps (Penaeus monodon) are able to survive and can be reared under various salinities, possibly by the cellular adaptation of their excretory system, particularly the antennal gland, which is known to regulate body fluid in crustaceans. We have investigated the morphological and biochemical alterations ...

journal_title：Cell and tissue research

authors： Buranajitpirom D,Asuvapongpatana S,Weerachatyanukul W,Wongprasert K,Namwong W,Poltana P,Withyachumnarnkul B

更新日期：2010-06-01 00:00:00

abstract：:Two dozen hybrid clones were produced by fusion of diploid embryonic stem (ES) cells positive for green fluorescent protein (GFP) with tetraploid fibroblasts derived from DD/c and C57BL-I(I)1RK mice. Cytogenetic analysis demonstrated that most cells from these hybrid clones contained near-hexaploid chromosome sets. Ad...

journal_title：Cell and tissue research

authors： Kruglova AA,Matveeva NM,Gridina MM,Battulin NR,Karpov A,Kiseleva EV,Morozova KN,Serov OL

更新日期：2010-06-01 00:00:00

abstract：:A striking feature of vestibular hair cells is the polarized arrangement of their stereocilia as the basis for their directional sensitivity. In mammals, each of the vestibular end organs is characterized by a distinct distribution of these polarized cells. We utilized the technique of post-fixation transganglionic ne...

journal_title：Cell and tissue research

authors： Maklad A,Kamel S,Wong E,Fritzsch B

更新日期：2010-05-01 00:00:00

abstract：:Adrenomedullin (AM) is a peptide hormone involved in the modulation of cellular growth, migration, apoptosis, and angiogenesis. These characteristics suggest that AM is involved in the control of neural stem/progenitor cell (NSPC) biology. To explore this hypothesis, we have obtained NSPC from the olfactory bulb of ad...

journal_title：Cell and tissue research

authors： Vergaño-Vera E,Fernández AP,Hurtado-Chong A,Vicario-Abejón C,Martínez A

更新日期：2010-04-01 00:00:00

abstract：:CD4+CD25+(high) regulatory T cells (Tregs) play a pivotal role in the control of the immune response. A growing body of evidence suggests the reduced function of these cells in autoimmune diseases, including type 1 diabetes (T1D). Restoration of their function can potentially delay further disease development. In the ...

journal_title：Cell and tissue research

authors： Glisic S,Ehlenbach S,Jailwala P,Waukau J,Jana S,Ghosh S

更新日期：2010-03-01 00:00:00

abstract：:Sipunculans, a small phylum of coelomated marine worms closely related to polychaete annelids, lack a true circulatory system. We have previously shown that the sipunculan Themiste petricola can form a cellular clot, without congealing, of cell-free coelomic fluid. The clot is formed by the aggregation of large granul...

journal_title：Cell and tissue research

authors： Cavaliere V,Papademetrio DL,Alvarez EM,Blanco GA

更新日期：2010-03-01 00:00:00

abstract：:Primmorphs (a three-dimensional sponge primary cell culture system) have been revealed to be a cell/tissue nano-factory for the production of tailor-made hybrid nanostructures. Growth of primmorphs is stimulated by the presence of a titanium alkoxide precursor tolerating titania (TiO2) concentrations up to 250 microM....

journal_title：Cell and tissue research

authors： Natalio F,Mugnaioli E,Wiens M,Wang X,Schröder HC,Tahir MN,Tremel W,Kolb U,Müller WE

更新日期：2010-02-01 00:00:00

abstract：:Antibodies against cartilage proteins are highly prevalent in the sera and synovial fluids of rheumatoid arthritis (RA) patients and also precede disease induction in various spontaneous and induced animal models of arthritis. These antibodies play an important role in the induction and perpetuation of the clinical di...

journal_title：Cell and tissue research

authors： Nandakumar KS

更新日期：2010-01-01 00:00:00

abstract：:Most myenteric neurons contain one of the two generating enzymes for major excitatory and inhibitory neurotransmitters: choline acetyltransferase (ChAT) or neuronal nitric oxide synthase (NOS). Two minor groups of myenteric neurons contain either both enzymes or neither. Our study had two aims: (1) to compare the prop...

journal_title：Cell and tissue research

authors： Beck M,Schlabrakowski A,Schrödl F,Neuhuber W,Brehmer A

更新日期：2009-10-01 00:00:00

abstract：:In amniotes, the developmental potentials of neural crest cells differ between the cranium and the trunk. These differences may be attributable to the different expression patterns of Hox genes between cranial and trunk neural crest cells. However, little is known about the factors that control Hox genes expression in...

journal_title：Cell and tissue research

authors： Ishikawa S,Ito K

更新日期：2009-09-01 00:00:00

abstract：:Taste buds and the peripheral nerves innervating them are two important components of the peripheral gustatory system. They require appropriate connections for the taste system to function. Neurotrophic factors play crucial roles in the innervation of peripheral sensory organs and tissues. Both brain-derived neurotrop...

journal_title：Cell and tissue research

authors： Ito A,Nosrat CA

更新日期：2009-09-01 00:00:00

abstract：:Light microscopy of native preparations, histology, and electron microscopy have revealed that Phlebotomus duboscqi belongs to a class of sand fly species with prompt development of the peritrophic matrix (PM). Secretion of electron-lucent fibrils, presumably chitin, starts immediately after the ingestion of a blood m...

journal_title：Cell and tissue research

authors： Sádlová J,Volf P

更新日期：2009-08-01 00:00:00

abstract：:To investigate the uptake and transport patterns of variously sized particles in Peyer's patches (PPs) of calves, intestinal loops were created in four newborn and two 2-month-old calves, and the loops were inoculated with various particles, including carbon black, fluorescein isothiocyanate (FITC)-labeled latex, FITC...

journal_title：Cell and tissue research

authors： Sein Lwin,Inoshima Y,Ueno H,Ishiguro N

更新日期：2009-07-01 00:00:00

abstract：:The fan-shaped body is the largest substructure of the central complex in Drosophila melanogaster. Two groups of large-field neurons that innervate the fan-shaped body, viz., F1 and F5 neurons, have recently been found to be involved in visual pattern memory for "contour orientation" and "elevation" in a rut-dependent...

journal_title：Cell and tissue research

authors： Li W,Pan Y,Wang Z,Gong H,Gong Z,Liu L

更新日期：2009-06-01 00:00:00

abstract：:The analysis of myenteric neurons is becoming increasingly important for the assessment of enteric nervous system injury and degeneration occurring in motor disorders of the gut. Limited information is presently available on the quantitative estimation of myenteric neurons and glial cells in paraffin-embedded colonic ...

journal_title：Cell and tissue research

authors： Ippolito C,Segnani C,De Giorgio R,Blandizzi C,Mattii L,Castagna M,Moscato S,Dolfi A,Bernardini N

更新日期：2009-05-01 00:00:00

abstract：:Inside the light organs of the bioluminescent (light-producing) crustacean Meganyctiphanes norvegica (krill), numerous capillaries drain haemolymph into the light-producing structure (lantern). We have investigated the arrangement and function of filamentous material found around the opening of the capillaries. These ...

journal_title：Cell and tissue research

authors： Krönström J,Karlsson W,Johansson BR,Holmgren S

更新日期：2009-05-01 00:00:00

abstract：:Glycosylation plays an essential role during development, in processes such as morphogen distribution, cell-to-cell communication, and extracellular matrix formation. Glycosylation is regulated during development in both a spatial and temporal manner. This study presents a detailed description of glycan distribution f...

journal_title：Cell and tissue research

authors： Yano H,Yamamoto-Hino M,Goto S

更新日期：2009-04-01 00:00:00

abstract：:The antennal lobe is the primary processing center for olfactory information in insects. To understand further the neural circuitry of this brain area, we have investigated the distribution of gamma-aminobutyric acid (GABA) and its colocalization with neuropeptides in the antennal lobe of the noctuid moth Heliothis vi...

journal_title：Cell and tissue research

authors： Berg BG,Schachtner J,Homberg U

更新日期：2009-03-01 00:00:00

abstract：:Their strategic location between blood and tissue and their constitutive properties allow endothelial cells (EC) to monitor the transport of plasma molecules, by employing bidirectional receptor-mediated and receptor-independent transcytosis and endocytosis, and to regulate vascular tone, cellular cholesterol and lipi...

journal_title：Cell and tissue research

authors： Sima AV,Stancu CS,Simionescu M

更新日期：2009-01-01 00:00:00

abstract：:Angiogenesis, the growth of new blood vessels, is required for a variety of normal proliferative processes. Furthermore, angiogenesis is well established as also playing an important role in neoplastic growth and metastasis. Numerous regulators of angiogenesis have been identified and characterized over the last few d...

journal_title：Cell and tissue research

authors： Crawford Y,Ferrara N

更新日期：2009-01-01 00:00:00

abstract：:The genes encoding transmembrane glycoproteins of the cadherin family, i.e., the Ca(2+)-dependent cell-cell adhesion molecules, are typically expressed in cell-type- or cell-lineage-specific patterns. One of them, vascular endothelial (VE)-cadherin, is widely considered to be specific for vascular endothelia in which ...

journal_title：Cell and tissue research

authors： Boda-Heggemann J,Régnier-Vigouroux A,Franke WW

更新日期：2009-01-01 00:00:00

abstract：:Large conductance calcium-activated potassium channels (BK(ca)) are crucial for the regulation of cerebral vascular basal tone and might be involved in cerebral vasodilation relevant to migraine and stroke. We studied the differential gene expression of mRNA transcript levels and protein expression of the BK(Ca) chann...

journal_title：Cell and tissue research

authors： Wulf H,Hay-Schmidt A,Poulsen AN,Klaerke DA,Olesen J,Jansen-Olesen I

更新日期：2008-12-01 00:00:00